Vicissitude

имя существительное 1) превратность 2) смена, чередование Например: The succession of light and darkness, the vicissitude of the seasons. — Смена дня и ночи, чередование времён года.

Большой англо-русский словарь

Vicissitude

noun Etymology: Middle French, from Latin vicissitudo, from vicissim in turn, from vicis change, alternation — more at week 1. a. the quality or state of being changeable; mutability b. natural change or mutation visible in nature or in human affairs 2. a. a favorable or unfavorable event or situation that occurs by chance; a fluctuation of state or condition Example: the vicissitudes of daily life b. a difficulty or hardship attendant on a way of life, a career, or a course of action and usually beyond one's control c. alternating change; succession

Merriam-Webster's Collegiate Dictionary